{"introPage":{"showIntroPage":false,"startButtonText":"Start Quiz","introduction":""},"progressType":"dots","passPercentage":50,"questions":[{"params":{"scoreShow":"Check","submit":"Submit","tryAgain":"Retry","scoreExplanation":"Correct answers give +1 point. Incorrect answers give -1 point. The lowest possible score is 0.","question":{"settings":{"size":{"width":1200,"height":800}},"task":{"elements":[{"x":1.757469244288225,"y":52.770448548812666,"width":16.27170474516696,"height":10.999297012302286,"dropZones":["2","0","1","3"],"type":{"library":"H5P.AdvancedText 1.1","params":{"text":"

The potential impacts upon Lulu and Nana are currently a matter of speculation. This is partly because we need to wait and see what happens, but also because there are very few details about their development in the public domain.<\/p>\n"},"subContentId":"0a206ea8-283a-42ad-8223-bab02709b396","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"backgroundOpacity":100,"multiple":false},{"x":26.36203866432337,"y":52.770448548812666,"width":16.27170474516696,"height":5.72688927943761,"dropZones":["0","1","2","3"],"type":{"library":"H5P.AdvancedText 1.1","params":{"text":"

Lula and Nana are acting as guineapigs for an untested intervention that they did not consent to.<\/p>\n"},"metadata":{"contentType":"Text","license":"U","title":"Untitled Text"},"subContentId":"6a0bc227-0915-4020-a235-3ff60a8b68e7"},"backgroundOpacity":100,"multiple":false},{"x":50.96660808435852,"y":52.770448548812666,"width":16.27170474516696,"height":7.044991212653779,"dropZones":["1","0","2","3"],"type":{"library":"H5P.AdvancedText 1.1","params":{"text":"

Unlike the use of gene editing in somatic cells, this germline gene editing makes a permanent change to germline cells that will be passed on to offspring.<\/p>\n"},"metadata":{"contentType":"Text","license":"U","title":"Untitled Text"},"subContentId":"c332be25-cf78-41c0-9b0a-f577eb70bd2e"},"backgroundOpacity":100,"multiple":false},{"x":75.57117750439367,"y":52.770448548812666,"width":16.27170474516696,"height":10.999297012302286,"dropZones":["2","0","1","3"],"type":{"library":"H5P.AdvancedText 1.1","params":{"text":"

A major concern is that attempts to cripple\u202fCCR5 gene may have resulted in off-target changes elsewhere in the girls' genomes. If so, these changes could cause a number of (as yet unknown) problems, including serious illnesses.<\/p>\n"},"metadata":{"contentType":"Text","license":"U","title":"Untitled Text"},"subContentId":"e55ab8ff-d224-41a2-bace-43b1cc779fa3"},"backgroundOpacity":100,"multiple":false},{"x":50.96660808435852,"y":71.24010554089709,"width":16.27170474516696,"height":12.317398945518454,"dropZones":["2","0","1","3"],"type":{"library":"H5P.AdvancedText 1.1","params":{"text":"

Several researchers who closely studied the images from the gene editing have cautioned that for Nana, the editing may have occurred after the embryo was past the one-cell stage. That means she could be a genetic mosaic so that some cells carry normal\u202fCCR5 and hence she would not be protected from HIV.<\/p>\n"},"metadata":{"contentType":"Text","license":"U","title":"Untitled Text"},"subContentId":"92988598-3754-4649-a607-23616a8fd363"},"backgroundOpacity":100,"multiple":false},{"x":26.36203866432337,"y":68.60158311345647,"width":16.27170474516696,"height":13.635500878734623,"dropZones":["3","0","1","2"],"type":{"library":"H5P.AdvancedText 1.1","params":{"text":"

Ethicists worry that gene editing, initially aimed at therapy, might lead to non-therapeutic enhancements, (like enhanced learning abilities). Indeed, the disabling of the CCR5 gene is known to enhance intelligence. This possibility opens a whole other debate about the ethics of enhancing desirable traits and suppressing undesirable ones.<\/p>\n"},"metadata":{"contentType":"Text","license":"U","title":"Untitled Text"},"subContentId":"6adcd640-0c57-4aac-ae83-03f1e6fe3fc9"},"backgroundOpacity":100,"multiple":false},{"x":1.7547231985940246,"y":79.15313396321918,"width":16.27170474516696,"height":8.363093145869946,"dropZones":["2","0","1","3"],"type":{"library":"H5P.AdvancedText 1.1","params":{"text":"

The CCR5 gene is involved in signalling and coordination of immune responses. Hence, immune system problems may arise if all these genes are disabled.<\/p>\n"},"metadata":{"contentType":"Text","license":"U","title":"Untitled Text"},"subContentId":"ee2d5e4e-fcc3-4837-b888-7616fb16d52d"},"backgroundOpacity":100,"multiple":false}],"dropZones":[{"x":1.7492311072056237,"y":2.6362409313311965,"width":17.13532513181019,"height":7.908611599297012,"correctElements":["1"],"showLabel":true,"backgroundOpacity":100,"tipsAndFeedback":{"tip":""},"single":false,"autoAlign":true,"label":"

Autonomy<\/strong><\/div>\n"},{"x":1.757469244288225,"y":23.7467018469657,"width":17.13532513181019,"height":9.22671353251318,"correctElements":["2"],"showLabel":true,"backgroundOpacity":100,"tipsAndFeedback":{"tip":""},"single":false,"autoAlign":true,"label":"
Future generations<\/strong><\/div>\n"},{"x":50.96386203866432,"y":2.6362409313311965,"width":35.58875219683655,"height":23.725834797891036,"correctElements":["0","3","4","6"],"showLabel":true,"backgroundOpacity":100,"tipsAndFeedback":{"tip":""},"single":false,"autoAlign":true,"label":"
Potential harms and benefits<\/strong><\/div>\n"},{"x":26.36203866432337,"y":2.638522427440633,"width":17.13532513181019,"height":23.725834797891036,"correctElements":["5"],"showLabel":true,"backgroundOpacity":100,"tipsAndFeedback":{"tip":""},"single":false,"autoAlign":true,"label":"
Slippery slope<\/strong><\/div>\n"}]}},"overallFeedback":[{"from":0,"to":100}],"behaviour":{"enableRetry":true,"enableCheckButton":true,"singlePoint":false,"applyPenalties":true,"enableScoreExplanation":true,"dropZoneHighlighting":"dragging","autoAlignSpacing":2,"enableFullScreen":false,"showScorePoints":true,"showTitle":true,"dragHandleVisibility":false},"grabbablePrefix":"Grabbable {num} of {total}.","grabbableSuffix":"Placed in dropzone {num}.","dropzonePrefix":"Dropzone {num} of {total}.","noDropzone":"No dropzone.","tipLabel":"Show tip.","tipAvailable":"Tip available","correctAnswer":"Correct answer","wrongAnswer":"Wrong answer","feedbackHeader":"Feedback","scoreBarLabel":"You got :num out of :total points","scoreExplanationButtonLabel":"Show score explanation","a11yCheck":"Check the answers. The responses will be marked as correct, incorrect, or unanswered.","a11yRetry":"Retry the task. Reset all responses and start the task over again.","localize":{"fullscreen":"Fullscreen","exitFullscreen":"Exit fullscreen"}},"library":"H5P.DragQuestion 1.15","metadata":{"contentType":"Drag and Drop","license":"U","title":"Sorting Exercise"},"subContentId":"fe5686b7-1c7a-45f2-8e31-12ec76ff0536"}],"disableBackwardsNavigation":false,"randomQuestions":false,"endGame":{"showResultPage":true,"showSolutionButton":true,"showRetryButton":true,"noResultMessage":"Finished","message":"Your result:","scoreBarLabel":"You got @finals out of @totals points","overallFeedback":[{"from":0,"to":100}],"solutionButtonText":"Show solution","retryButtonText":"Retry","finishButtonText":"Finish","submitButtonText":"Submit","showAnimations":false,"skippable":false,"skipButtonText":"Skip video"},"override":{"checkButton":true},"texts":{"prevButton":"Previous question","nextButton":"Next question","finishButton":"Finish","submitButton":"Submit","textualProgress":"Question: @current of @total questions","jumpToQuestion":"Question %d of %total","questionLabel":"Question","readSpeakerProgress":"Question @current of @total","unansweredText":"Unanswered","answeredText":"Answered","currentQuestionText":"Current question","navigationLabel":"Questions"}}

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A Case Of Gene Editing In Human Embryos cont.